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南科大医学院
官方公众号

Cao Huiling

Research Associate Professor

88018408

caohl@sustech.edu.cn

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个人简介

研究领域

◆Skeletal development and homeostasis

◆Osteoporosis

◆Osteoarthritis

◆Tumor skeletal metastases


教育背景

◆1999.09-2004.07 Department of Laboratory Medicine, Tianjin Medical University  MD

◆2004.09-2010.07 Joint Training Program of Chinese and American Doctor            PhD


工作经历

◆2010.07- 2011.08    University of Pittsburgh School of Medicine   Post-Doc

◆2014.11- 2016.12    Dept of Biology, SUSTech                 Engineer

2017.01- 2020.02      Dept of Biology, SUSTech                 Research associate professor

◆2020.03-                  School of Medicine, SUSTech           Research associate professor


获奖情况及荣誉

◆Excellent PhD Graduate Award, Tianjin medical university, China, 2010

◆ASBMR Young Investigator Award, 2011

◆Young Investigator Award, ICBMR & 11th International Osteoporosis Symposium, 2011

◆Chinese National Excellent Doctoral Dissertation nomination, 2012

◆Excellent Doctoral Dissertation Award

◆Shenzhen peacock scholar (Class C) (2015)

◆ASBMR Young Investigator Travel Grant, 2016

◆ICMRC-2017 Young Investigator Award

◆ASBMR Plenary poster, 2017

◆Webster Jee Travel Award, The 10th Annual Meeting of the National Osteoporosis and Bone and Mineral Research, the Chinese Medical Association, 2018


近年代表文章

1. Yu S, Franceschi RT, Luo M, Fan J, Jiang D, Cao H, Lai Y, Zhang J, Patrene K, Hankenson KD, Roodman GD, Xiao G*. Critical role of activating transcription factor 4 in the anabolic actions of PTH in bone. PLoS One. 2009, Oct 23; 4(10):e7583. PMCID: PMC2762317
2. Cao H, Yu S, Yao Z, Galson DL, Jiang Y, Zhang X, Fan J, Lu B, Guan Y, Luo M, Lai Y, Zhu, Y, Kurihara N, Patrene K, Roodman GD, Xiao G*. Activating transcription factor 4 regulates osteoclast differentiation in mice. J Clin Invest. 2010 Aug 2; 120(8):2755-66. PMCID: PMC2912190
3. Yang S, Xu H, Yu S, Cao H, Fan J, Ge C, Fransceschi RT, Dong H, Xiao G*. Foxo1 mediates IGF1/Insulin regulation of osteocalcin expression by antagonizing Runx2 in osteoblasts, J Biol Chem, 2011. PMID: 21471200.
4. Xiao G, Cheng H, Cao H(co-first author), Chen K, Tu Y, Yu S, Jiao H, Yang S, Im HJ, Chen D, Chen J, Wu C. Critical role of filamin-binding LIM protein 1 (FBLP-1)/migfilin in regulation of bone remodeling. J Biol Chem, 2012. PMID: 22556421
5. Teramachi J, Hiruma Y, Ishizuka S, Ishizuka H, Brown JP, Michou L, Cao H, Galson DL, Subler MA, Zhou H, Dempster DW, Windle JJ, Roodman GD, Kurihara N. Role of ATF7-TAF12 interactions in the VDR hyper-sensitivity of osteoclast precursors in Paget’s disease. J Bone Miner Res. 2013. PMID:23426901
6. Zhu K, Jiao H, Li S, Cao H, Galson DL, Zhao Z, Zhao X, Lai Y, Fan J, Im HJ, Chen D, Xiao G*. ATF4 regulates bone angiogenesis during development and in hypoxia in mice. J Bone Miner Res. 2013. PMID:23649506
7. Cao H, Zhu K, Qiu L, Li S, Niu H, Yang S, Zhao Z, Hao M, Anderson JL, Fan J, Roodman GD, Xiao G. Critical role of AKT protein in myeloma-induced osteoclast formation and osteolysis.  J Biol Chem, 2013. PMID:24005670
8. Qin T, Xu G, Qi J, Yang G, Zhang K, Liu H, Xu L, Xiang R, Xiao G, Cao H, Wei Y, Zhang Q, Li L. Tumor necrosis factor superfamily member 15 (Tnfsf15) facilitates lymphangiogenesis via upregulation of Vegfr3 gene expression in lymphatic endothelial cells. J Pathol. 2015. PMID: 26096340
9. Wu C, Jiao H, Lai, Y Zheng W, Chen K, Deng W, Song P, Zhu K, Cao H, Galson DL, Fan J, Im HJ, Liu Y, Chen J, Chen D, Xiao G. Kindlin-2 controls TGF-β signaling and Sox9 expression to regulate chondrogenesis. Nat Commun. 2015 Jul 7;6:7531. doi: 10.1038/ncomms8531. PMID: 26151572
10. Xu H, Cao H, Xiao G. Signaling via PINCH: functions, binding partners and implications in human diseases. Gene. 2016 Aug 30. PMID: 27590440