Dr. Fu, Associate Professor, Doctoral Supervisor, Research Team Leader, Southern University of Science and Technology. Dr. Fu has been engaged in research on intestinal pathogens and symbiotic bacteria for a long time before returning to China. He has achieved a series of landmarks around the pathogenesis of intestinal bacteria, bacterial secretion system, mechanism of interaction between bacteria in the host, and host immune activation. Results. In recent years, he has published 16 research papers in well-known journals such as Cell Host & Microbe, Science Translational Medicine, Proc Natl Acad Sci USA, Journal of Immunology, and has served as a reviewer for many well-known journals for a long time.
1、Intestinal pathogens and symbiotic bacteria,
2、The new mechanism of pathogenicity of intestinal bacteria
3、The in vivo function and transformation of bacterial secretion system, the mechanism of interaction between bacteria in the host, and the activation of host immune system.
1、2001.09-2005.06 Bachelor ,Jiangnan University
2、2006.09-2013.06 Doctor , Nankai University
3、2009.09-2013.05 Joint Doctor of Education ,Harvard University
1、2005.07-2006.08 Technician, Nankai University
2、2008.06-2009.01 Visiting Scholar , School of Public Health,Harvard University
3、2013.07-2018.06 Postdoctoral researcher , School of Medicine,Harvard University
4、2018.07-2019.06 Assistant researcher, School of Medicine,Harvard University
5、2019.06-2020.12,Assistant professor / PhD Tutor, Southern University of Science and Technology
6、2020.12-present,Associate professor / PhD Tutor, Southern University of Science and Technology
1、National talent plan
2、Overseas High-Caliber Personnel (Level-B) in Shenzhen
3、Fogarty Global Health Fellowship
1、magazine editor of Bio-Protocol
Cai, Q., D. Huang, P. Ou, H. Yu, Z. Zhu, Z. Xia, Y. Su, Z. Ma, Y. Zhang, Z. Li, Q. He, L. Liu, Y. Fu# and J. Chen# (2020.03.31). COVID-19 in a designated infectious diseases hospital outside Hubei Province, China. Allergy. (IF: 6.771)
# Co-corresponding author
Juanjuan Zhao,Quan Yuan,Haiyan Wang,Wei Liu,Xuejiao Liao, Yingying Su,Xin Wang, Jing Yuan, Tingdong Li,Jinxiu Li,Shen Qian, Congming Hong, Fuxiang Wang, Yingxia Liu, Zhaoqin Wang,Qing He, Zhiyong Li,Bin He, Tianying Zhang,Yang Fu, Shengxiang Ge, Lei Liu, Jun Zhang ,Ningshao Xia, Zheng Zhang(2020.03.28). Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019. Clin Infect Dis. 2020 Mar 28:ciaa344. doi: 10.1093/cid/ciaa344 (IF:9.17)
Juan Xue, Xing Pan, Ting Peng, Meimei Duan , Lijie Du , Xiaohui Zhuang, Xiaobin Cai, Xueying Yi , Yang Fu , Shan Li .(2020.05.05)Auto Arginine-GlcNAcylation Is Crucial for Bacterial Pathogens in Regulating Host Cell Death. Front Cell Infect Microbiol. 2020 May 5;10:197. doi: 10.3389/fcimb.2020.00197
Xuelan Zhou , Fanglin Zhong , Cheng Lin , Xiaohui Hu , Yan Zhang, Bing Xiong , Xiushan Yin , Jinheng Fu , Wei He , Jingjing Duan , Yang Fu , Huan Zhou , Peter J McCormick , Qisheng Wang , Jian Li , Jin Zhang .(2020.9.1)Structure of SARS-CoV-2 main protease in the apo state. Sci China Life Sci. doi: 10.1007/s11427-020-1791-3
Jianghong An, Xuejiao Liao, Tongyang Xiao, Shen Qian, Jing Yuan, Haocheng Ye, Furong Qi, Chengguang Shen, Lifei Wang, Yang Liu, Xiaoya Cheng, Na Li, Qingxian Cai, Fang Wang,Jun Chen, Guojun Li, Qiu’e Cai, Yingxia Liu, Yunfang Wang, Feng Zhang, Yang Fu, Qing He, Xiaohua Tan, Lei Liu, Zheng Zhang. (2020.9.4) Clinical characteristics of the recovered COVID-19 patients with re-detectable positive RNA test. Ann Transl Med 2020;8(17):1084 | http://dx.doi.org/10.21037/atm-20-5602
Jian Li, Xuelan Zhou, Yan Zhang, Fanglin Zhong, Cheng Lin, Peter J.McCormick, Feng Jiang, Jun Luo, Huan Zhou, Qisheng Wang, Yang Fu,Jingjing Duan, Jin Zhang. (2020.9.22) Crystal structure of SARS-CoV-2 main protease in complex with the naturalproduct inhibitor shikonin illuminates a unique binding mode. Science Bulletin https://doi.org/10.1016/j.scib.2020.10.018
Fu Y, Ho BT, & Mekalanos JJ (2018.02.14) Tracking Vibrio cholerae Cell-Cell Interactions during Infection Reveals Bacterial Population Dynamics within Intestinal Microenvironments. Cell host & microbe 23(2):274-281 e272.
(IF: 17.87, Ranked 1st in Microbiology, Cell Press Sub-Publication)
Ho BT*, Fu Y*, Dong TG, & Mekalanos JJ (2017.07.17) Vibrio cholerae type 6 secretion system effector trafficking in target bacterial cells. Proceedings of the National Academy of Sciences of the United States of America 114(35):9427-9432.
(IF: 9.5, Ranked 3rd in Life Science, Health & Medical Sciences) * Co-First Authors
Fu Y, Waldor MK, & Mekalanos JJ (2013.12.11) Tn-Seq analysis of Vibrio cholerae intestinal colonization reveals a role for T6SS-mediated antibacterial activity in the host. Cell host & microbe 14(6):652-663.
(IF: 17.87, Ranked 1st in Microbiology, Cell Press Sub-Publication, Cited By 125)
Fu Y# & Mekalanos JJ# (2014.06.05) Infant Rabbit Colonization Competition Assays. Bio Protoc 4(11). # Co-Corresponding Authors
Altindis E, Fu Y, & Mekalanos JJ (2014.02.28) Proteomic analysis of Vibrio cholerae outer membrane vesicles. Proceedings of the National Academy of Sciences of the United States of America 111(15): E1548-1556. (IF: 9.5, Ranked 3rd in Life Science, Health & Medical Sciences [general], Cited by 74)
Sanchez-Larrayoz AF, Elhosseiny, NM, Chevrette MG, Fu Y, Giunta P, Spallanzani RG, Ravi K, Pier GB, Lory S, and Maira-Litran T (2017.08.30) Complexity of Complement Resistance Factors Expressed by Acinetobacter baumannii Needed for Survival in Human Serum. J Immunol 199, 2803-2814. (IF: 4.54, Ranked 6th in Immunology)
Roux, D, Danilchanka, O, Guillard, T, Cattoir, V, Aschard, H, Fu, Y, Angoulvant, F, Messika, J, Ricard, JD, Mekalanos, JJ, et al. (2015.07.22). Fitness cost of antibiotic susceptibility during bacterial infection. Sci Transl Med 7, 297ra114. (IF: 16.71, Ranked 10th in Health & Medical Sciences [general], Science Sub-Publication, Cited By 63)
Liao Q, Strong A. J, Liu Y, Meng P, Fu Y, Touzjian N, Shao Y, Zhao Z, Lu Y (2012.01.17) HIV vaccine candidates generate in vitro T cell response to putative epitopes in Chinese-origin rhesus macaques. Vaccine. 30(9): 1601-1608. (IF: 3.3, Ranked 3rd in Virology)
Xiangke Duan, Yang Fu, and Liang Yang. Chapter 5Molecular and Systems Biology Approaches for Analyzing Drug-Tolerant Bacterial Persister Cells
https://doi.org/10.1007/978-3-030-53024-2_5