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南科大医学院
官方公众号

Wang Zhuo

Research Assistant Professor

wangz3@sustech.edu.cn

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个人简介

Zhuo WANG., Ph.D., Research Assistant Professor in the School of Medicine, Southern University of Science and Technology. She received a Ph.D. in cell biology from The Hong Kong Polytechnic University. She completed a two-year post-doctoral training in liver diseases at SUSTech. Her research interests include studying the pathogenesis of liver diseases and investigating novel molecular-targeted therapeutic strategies for liver diseases.

教育背景

Ph.D. (2009-2014)

Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University

B.Sc. (2005-2009)

School of Pharmacy, Wuhan University


工作经历

Research Assistant Professor (2019-now)

School of Medicine, Southern University of Science and Technology

Research Associate (2018-2019)

Department of Biology, Southern University of Science and Technology

Postdoctoral Fellow (2016-2018)

Department of Biology, Southern University of Science and Technology

Postdoctoral Research Associate (2014-2015)

Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University


近年代表文章

1. Zhuo Wang#*, Ming Yan#, Jia’an Li, Jiafu Long, Hongmin Zhang*. Dual functions of STAT in LPS-induced angiogenesis of hepatocellular carcinoma. Biochimica et Biophysica Acta-molecular cell research. 2019 Apr;1866(4):566-574

2. Zhuo Wang*, Jia’an Li, Wen’ang Xiao, Jiafu Long, Hongmin Zhang*. STAT3 inhibitor S3I-201 suppresses the fibrogenesis and angiogenesis in liver fibrosis. Laboratory Investigation. 2018; 96(12): 1600-12

3. Lei H, Yan J, Yu J, Liu Y, Wang Z, Xu Z, Ye T. Total Synthesis and Stereochemical Reassignment of Mandelalide A. Angewandte Chemie International Edition. 2014, 53, 6533-6537

4. Wang X, Lv C, Liu J, Tang L, Feng J, Tang S, Wang Z, Liu Y, Meng Y, Ye T, Xu Z. Total Synthesis of the Proposed Structure for Itralamide B. Synlett, 2014, 25, 1014

5. Wang Z, Liu Y, Wang J, Lam W, Kwong S, Li F, Friedman SL, Zhou S, Ren Q, Xu Z, Wang X, Ji L, Tang S, Zhang H, Lui EL, Ye T. A histone deacetylase inhibitor, largazole, decreases liver fibrosis and angiogenesis by inhibiting transforming growth factor-β and vascular endothelial growth factor signalling. Liver Int. 2013; 33(4): 504-15

6. Long B, Tang S, Chen L, Qu S, Chen B, Liu J, Maguire AR, Wang Z, Liu Y, Zhang H, Xu Z, Ye T.. Total Synthesis of Padanamides A and B. Chem. Commun. 2013, 49, 2977-9

7. Liu H, Liu Y, Wang Z, Xing X, Maguire AR, Luesch H, Zhang H, Xu Z, Ye T. Total Synthesis and Biological Evaluation of Grassypeptolide A. Chemistry-A European Journal, 2013, 19. 6774-84

8. Dai L, Liu Y, Liu J, Wen X, Xu Z, Wang Z, Sun H, Tang S, Maguire AR, Quan J, Zhang H, Ye T. A Novel CyclinE/CyclinA-CDK2 Inhibitor Targets p27Kip1 Degradation, Cell Cycle Progression and Cell Survival: Implications in Cancer Therapy. Cancer Letters, 2013, 333, 103-12

9. Liu J, Ma X, Liu Y, Wang Z, Kwong S, Ren Q, Tang S, Meng Y, Xu Z, Ye T. Total Synthesis and Stereochemical Revision of Burkholdac A. Synlett, 2012, 19, 783-787

10. Dai L, Chen B, Lei H, Wang Z, Liu Y, Xu Z, Ye T. Total Synthesis and Stereochemical Revision of Lagunamide A. Chem. Commun. 2012, 48, 8697-8699.

11. Liu Y, Wang Z, Kwong SQ, Lui EL, Friedman SL, Li FR, Lam RW, Zhang GC, Zhang H, Ye T. Inhibition of PDGF, TGF-β, and Abl signaling and reduction of liver fibrosis by the small molecule Bcr-Abl tyrosine kinase antagonist Nilotinib. J Hepatol. 2011; 55(3):612-25

12. Jin Y, Liu Y, Wang Z, Kwong S, Xu Z, Ye T. Total synthesis of sintokamide C. Org Lett. 2010;12(5):1100-3