南科大医学院
官方公众号
Peng Wang, Chair Professor and doctoral supervisor of School of Medicine of Southern University of Science and Technology (SUSTech), distinguished Professor of Ministry of Education, State Specially Recruited Expert, Ohio Eminent Scholar, and Georgia Research Alliance (GRA) Eminent Scholar. He got his Bachelor degree from Nankai University in 1984 and obtained his PhD in University of California, Berkeley in 1990, and then worked as postdoc in University of California Berkeley and Scripps Research Institute respectively from 1991-1994. He started his research group in University of Miami as an assistant professor in 1994 and promoted to Professor of Wayne State University and Chair Professor of Georgia State University. He has served as the Dean of the school of pharmacy, Nankai University and has founded the national sugar Engineering Technology Research Center, and served as the director of the sugar research center. He has won a number of domestic and international awards, undertaken a number of scientific research projects in China and the United States, hold 8 invention patents, and published 6 academic monographs and more than 430 papers in international academic journals, with the h-index values of 57 (Google Scholar) and 47 (web of Science) respectively. Besides, he is the deputy editor or editorial board member of many international academic journals. As an expert in the field of sugar chemistry, his research interests include pharmaceutical chemistry, sugar biology, chemical biology, glycoproteomics, etc.; as well as biological engineering of natural products, enzyme catalytic reaction, green chemistry, chemical biology of active nitrogen and oxygen in life.
Glycoscience on glycobiolgy, glycochemistry, glycoanalysis, glycomics, Carbohydrate chemistry, carbohydrate biology and Glycomics
Pharmaceutical chemistry, green chemistry, and medicinal chemistry of natural products
Chemical biology of active nitrogen and oxygen in life
Endowed Professor 9/2019 - present
College of Pharmacy, South University of Science and Technology (SUSTech)
An endowed chair professor in pharmacy
Professor 8/2011-7/2019
Department of Chemistry, Georgia State University (GSU)
Georgia Research Alliance (GRA) Eminent Scholar
An endowed chair professor in carbohydrate chemistry and glycobiology
Chair 4/2015-6/2018
Department of Chemistry, Georgia State University (GSU)
Professor 9/2003-8/2011
Departments of Biochemistry and Chemistry, The Ohio State University (OSU)
Ohio Eminent Scholar, An endowed chair professor in macromolecular structure and function
Member The Dorothy M. Davis Heart & Lung Research Institute, OSU
Member The Center for Microbial Interface Biology (CMIB), OSU
Member The Ohio State University Comprehensive Cancer Center, OSUCCC
Professor 8/2001-9/2003
Department of Chemistry, Wayne State University
Joint Professor
Barbara Ann Karmanos Cancer Institute, The Detroit Medical Center, Wayne State University
Member Institute for Drug Design, Wayne State University
Associate Professor 8/1997-8/2001
Department of Chemistry, Wayne State University
Assistant Professor 8/1994-8/1997
Department of Chemistry, University of Miami.
Postdoctoral Fellow 2/1992-8/1994
Scripps Research Institute
Advisor: Dr. Chi-Huey Wong
Postdoctoral Fellow 1/1991-2/1992
University of California, Berkeley
Advisor: Dr. Mark D. Bednarski
Research Assistant 5/1987-12/1990
University of California, Berkeley
Advisor: Dr. Mark D. Bednarski & Dr. Andrew Streitwieser
2012 The American Association for the Advancement of Science (AAAS) Fellow
2009 The Recipient of Grand Challenges Exploration Award Phase I from the Bill & Melinda Gate Foundation
2002 The Horace S. Isbell Award from the American Chemical Society, Division of Carbohydrate Chemistry (only one such award is given each year by the American Chemical Society Division of Carbohydrate Chemistry to a scientist of less than 41-years-old who has made outstanding contributions to the field of carbohydrate chemistry or glycobiology)
2000 Co-recipient of the Presidential Green Chemistry Challenge Award Honoring Professor C. -H.Wong
2000 The Metro Detroit’s Creator from Crain’s Detroit Business
1999 Camille Dreyfus Teacher-Scholar Award from The Camille and Henry Dreyfus Foundation (criteria for this award include an independent body of scholarship attained within the first five years of their appointment as independent researchers, and a demonstrated commitment to education, signaling the promise of continuing outstanding contributions to both research and teaching. Each year 10 to 15 awards are given.)
1996-01 National Institutes of Health First Independent Research Support and Transition (FIRST)
1988 NATO Fellowship from NATO Advanced Study Institute
Member of Editorial Board of Journal of Biological Chemistry 2014-present
Associate Editor of Organic Chemistry Frontiers 2018-present
Member of Editorial Board of American Journal of Biomedical Sciences 2008-present
Member of Editorial Board of Carbohydrate Research 2005-2012
Member of Editorial Board of Applied and Environmental Microbiology 2003-present
Member of Editorial Board of Marine Drugs 2002-present
Regional Editor, Current Organic Chemistry 2002-present
Member of Editorial Board of Medicinal Research Reviews 2001-present
h index factor 57 (Google Scholar) and 47 (Web of Science) (Orcid Id: 0000-0003-3335-6794)
440. Ma, J., Li, L., Yue, K., Li, Y., Liu, H., Wang, P.G, Wang, C, Wang, J., Luo, W., Xie, S.“Bromocoumarinplatin, targeting simultaneously mitochondria and nuclei with p53 apoptosis pathway to overcome cisplatin resistance.” 2020, Bioorg Chem. Mar 20;99:103768.
439. Purohit S, Ferris DG, Alvarez M, Tran PMH, Tran LKH, Mysona DP, Hopkins D, Zhi W, Dun B, Wallbillich JJ, Cummings RD, Wang, P.G, She JX. “Better survival is observed in cervical cancer patients positive for specific anti-glycan antibodies and receiving brachytherapy.” 2020, Gynecol Oncol. Apr;157(1):181-187.
438. Wang S, Rong Y, Wang Y, Kong D, Wang, P.G, Chen M, Kong Y. “Homogeneous production and characterization of recombinant N-GlcNAc-protein in Pichia pastoris.” 2020, Microb Cell Fact. Jan 13;19(1):7.
437. Li L, Guan W, Zhang G, Wu Z, Yu H, Chen X, Wang, P.G. “Microarray analyses of closely related glycoforms reveal different accessibilities of glycan determinants on N-glycan branches.” 2019, Glycobiology. Dec 6. pii: cwz100.
436. Liu H, Ma J, Li Y, Yue K, Li L, Xi Z, Zhang X, Liu J, Feng K, Ma Q, Liu S, Guo S, Wang, P.G, Wang C, Xie S. “Polyamine-Based Pt(IV) Prodrugs as Substrates for Polyamine Transporters Preferentially Accumulate in Cancer Metastases as DNA and Polyamine Metabolism Dual-Targeted Antimetastatic Agents.” 2019, Med Chem. Dec 26;62(24):11324-11334.
435. Liu L, Li L, Ma C, Shi Y, Liu C, Xiao Z, Zhang Y, Tian F, Gao Y, Zhang J, Ying W, Wang, P.G, Zhang L7. “O-GlcNAcylation of Thr12/Ser56 in short-form O-GlcNAc transferase (sOGT) regulates its substrate selectivity.” 2019, Biol Chem. Nov 8;294(45):16620-16633.
434. Wang, P.G, Li YT, Pan Y, Gao ZZ, Guan XW, Jia L, Liu FT. “Lower expression of Bax predicts poor clinical outcome in patients with glioma after curative resection and radiotherapy/chemotherapy.” 2019, Neurooncol. Jan;141(1):71-81.
433. Liu, J., Li, S., Aslam, N.A., Zheng, F., Yang, B., Cheng, R., Wang, N., Rozovsky, S., Wang, P.G., Wang, Q. and Wang, L..“Genetically Encoding Photocaged Quinone Methide to Multitarget Protein Residues Covalently in Vivo.” 2019, Journal of the American Chemical Society,141 (24) 9458-9462
432. Zhang, P., Liu, P., Xu, Y., Liang, Y., Wang, P.G. and Cheng, J., "N-acetyltransferases from three different organisms displaying distinct selectivity toward hexosamines and N-terminal amine of peptides." 2019. Carbohydrate research 472: 72-75.
431. Davies-Bolorunduro, O.F., Adeleye, I.A., Akinleye, M.O. and Wang, P.G.. “Anticancer potential of metabolic compounds from marine actinomycetes isolated from Lagos Lagoon sediment.” 2019, J Pharm Anal. Jun, 9(3):201-208. PMID:31297298
430. Wu, Q., Liu, F., Song, Y., Meng, Q., Zhang, X., Li, H., Sun, J., Gao, H., Wang, P.G., Kong, Y. and Chen, M. “A new strategy for high-throughput identification of human gut microbiota containing specific monosaccharide.” 2019, Sci China Life Sci. Jul, 62(7):985-987. PMID:31098892
429. Yang, B., Wang, N., Schnier, P.D., Zheng, F., Zhu, H., Polizzi, N.F., Ittuveetil, A., Saikam, V., DeGrado, W., Wang, Q. and Wang, P.G.. “Genetically Introducing Biochemically Reactive Amino Acids Dehydroalanine and Dehydrobutyrine in Proteins.” 2019, Journal of the American Chemical Society, PMID:31038942
428. Wei, M, Wang, P.G.. “Desialylation in physiological and pathological processes: New target for diagnostic and therapeutic development.” 2019, Prog Mol Biol Transl Sci, 162:25-57. PMID:30905454
427. Wang, H, Yang, X, Zhao, C, Wang, P.G., Wang, X. “Glucose-conjugated platinum(IV) complexes as tumor-targeting agents: design, synthesis and biological evaluation.” 2019, Bioorg Med Chem. Apr 15, 27(8):1639-1645. PMID:30852077
426. Wang, J., Li, S., Zang, L., Zhu, H., Guo, J., Zhang, J., Wen, L., Chen, Y., Li, Y., Chen, X. and Wang, P.G.. “Production of Glycopeptide Derivatives for Exploring Substrate Specificity of Human OGA Toward Sugar Moiety.” 2019, Front Chem. Jan 14, 6:646. PMID:30693278
425. Hou, J., Pan, Y., Zhu, D., Fan, Y., Feng, G., Wei, Y., Wang, H., Qin, K., Zhao, T., Yang, Q. and Zhu, Y., Che, Y., Liu, Y., Cheng, J., Kong, D., Wang P.G., Shen, J., Zhao, Q.. “Targeted delivery of nitric oxide via a 'bump-and-hole'-based enzyme-prodrug pair.” 2019 Nature Chemical Biology Feb;15(2):151-160. PMID:30598545
424. Li, X., Ding, L., Li, X., Zhu, H., Gashash, E.A., Li, Z., Wang, P.G. and Ma, C.. “An integrated proteomic and glycoproteomic study for differences on glycosylation occupancy in rheumatoid arthritis.” 2019, Analytical and bioanalytical chemistry, pp.1-8.
423. Zhang, P., Liu, P., Xu, Y., Liang, Y., Wang, P.G. and Cheng, J.. “N-acetyltransferases from three differen t organisms displaying distinct selectivity toward hexosamines and N-terminal amine of peptides.” 2019, Carbohydrate Research, 472, pp.72-75.
422. Ma, Z., Wang, P. G.. “RecET Direct Cloning of Polysaccharide Gene Cluster from Gram-Negative Bacteria.” In Bacterial Polysaccharides. 2019, Bacterial Polysaccharides. Humana Press, pp 15-23.
421. Hu, X., Pang, X., Wang, P.G. and Chen, M.. “Isolation and characterization of an antioxidant exopolysaccharide produced by Bacillus sp. S-1 from Sichuan Pickles.” 2019, Carbohydrate Polymers, 204, pp.9-16.
420. Wang, J., Zhang, D., Wen, Y., Cao, X., Ma, J. and Wang, P.G.. “Efficient chemoenzymatic synthesis of UDP-α-6-N3-glucose.” 2019, Bioorganic & Medicinal Chemistry Letters. 29 (9), 1148-1151
419. Aloor A, Zhang J, Gashash E, Parameswaran A, Chrzanowski M, Ma C, Diao Y, Wang P.G, Xiao W. “Site-Specific N-Glycosylation on the AAV8 Capsid Protein” 2018, Viruses 10, 644.
418. Hu, X., Yang, C., Wang, P.G. and Zhang, G.L.. “ADP-heptose: A new innate immune modulator.” 2018, Carbohydrate Research. 473, pp. 123-128.
417. Zhang, J., Chen, C., Gadi, M.R., Gibbons, C., Guo, Y., Cao, X., Edmunds, G., Wang, S., Liu, D., Yu, J. and Wen, L., Wang, P.G.. “Machine‐Driven Enzymatic Oligosaccharide Synthesis by Using a Peptide Synthesizer.” 2018, Angewandte Chemie International Edition, 130 (51), 16880-16884.
416. Ma, Z., Zhang, H., Li, L., Chen, M. and Wang, P.G.. “Direct Cloning of Bacterial Surface Polysaccharide Gene Cluster for One-Step Production of Glycoconjugate Vaccine.” 2018, ACS Infectious Diseases. 5 (1), pp 74–78.
415. Wen, L., Edmunds, G., Gibbons, C., Zhang, J., Gadi, M.R., Zhu, H., Fang, J., Liu, X., Kong, Y. and Wang, P.G.. “Toward Automated Enzymatic Synthesis of Oligosaccharides.” 2018, Chemical Reviews, 118(17), pp.8151-8187.
414. Ma, Z., Zhang, H., Wang, P.G., Liu, X.W. and Chen, M.. “Peptide adjacent to glycosylation sites impacts immunogenicity of glycoconjugate vaccine.” 2018, Oncotarget, 9(1), p.75.
413. Li, S., Wang, J., Zang, L., Zhu, H., Guo, J., Zhang, J., Wen, L., Chen, Y., Li, Y., Chen, X. and Wang, P.G.. “Production of Glycopeptide Derivatives for Exploring Substrate Specificity of Human OGA Toward Sugar Moiety.” 2018, Frontiers in Chemistry, 6.
411. Ma, J., Liu, H., Xi, Z., Hou, J., Li, Y., Niu, J., Liu, T., Bi, S., Wang, X., Wang, C. and Wang, J., Wang, P.G.. “Protected and de-protected platinum (IV) glycoconjugates with GLUT1 and OCT2-mediated selective cancer targeting: demonstrated enhanced transporter-mediated cytotoxic properties in vitro and in vivo.” 2018, Frontiers in Chemistry, 6.
410. Yu, H., Santra, A., Li, Y., McArthur, J.B., Ghosh, T., Yang, X., Wang, P.G. and Chen, X., . “Streamlined chemoenzymatic total synthesis of prioritized ganglioside cancer antigens.” 2018 Organic & Biomolecular Chemistry, 16(22), pp.4076-4080.
409. Wang, J., Greenway, H., Li, S., Wei, M., Polizzi, S. J., & Wang, P. G.. “Facile and Stereo-Selective Synthesis of UDP-α-D-xylose and UDP-β-L-arabinose Using UDP-Sugar Pyrophosphorylase”. 2018, Frontiers in Chemistry, May, Volume 6, Article 163.
408. Wang, N.; Yang, B.; Fu, C.; Zhu, H.; Zheng, F.; Kobayashi, T.;Liu, J.; Li,S.; Ma, C.; Wang, P. G.; Wang, Q.;Wang, L,; “Genetically Encoding Fluorosulphate-L-Tyrosine to React with Lysine, Histidine and Tyrosine via SuFEx in proteins in vivo” 2018, Journal of American Chemical Society 140(15), 4995-4999.
407. Wang, S.; Zhang, Q.; Chen, C.; Guo, Y.; Gadi, M.R.; Yu, J.; Westerlind, U.; Liu,Y.; Cao, X.; Wang, P. G.; Li, L.; “Facile Chemoenzymatic Synthesis of O-mannosyl glycans” 2018, Angewandte Chemie International Edition 57(30), 9268-9273.
406. Wen, L.; Gadi, M. R.; Zheng, Y.; Gibbons, C.; Kondengaden, S.; Zhang, J.; Wang, P. G. “Chemoenzymatic Synthesis of Unnatural Nucleotide Sugars for Enzymatic Biorthogonal Labeling” ACS Catalysis 2018, 8, 7659-7666.
405. Yu, B.; Li, S.; Wang, J.; Zheng, Y.; Zhang, H.; Walker, M.-J.; Yuan, Z.; Zhu, H.; Zhang, J.; Wang, P. G.; Wang, B. “Biomarker-based Metabolic Labeling for Redirected and Enhanced Immune Response” ACS Chemical Biology 2018, 13(6), 1686-1694.
404. Li, J.; Li, S.; Li, Q.; Long, J.; Ma, C.; Guo, J.; Ding, Y.; Yan, C.; Li, L .;Wu, Z; Zhu, H.; Li, K.-K.; Wen, L; Zhang, Q.; Ivanov, I.; Luo, M.; Xi, R.; Long, H.; Wang, P. G.; Chen, Y. “Natural Product Micheliolide (MCL) Irreversibly Activates PKM2 and Suppresses Leukemia” Journal of Medicinal Chemistry 2018, 61, 4155−4164.
402. Purohit, S.; Li, T. -H.; Guan, W. -Y.; Song, X. -Z.; Song, J.; Tian, Y.’ Li, L.; Sharma, A.; Dun, B. -Y.; Mysona, D.; Ghamande, S.’ Rungruang, B.; Cummings, R. D.; Wang, P. G.; She, J. -X. “Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins” Nature Communications 2018, 9, 258.
401. Zhang, Q.; Ma, C.; Gearing, M.; Wang, P. G.; Chin, L.-S.; Li, L. “Integrated proteomics and network analysis identifies protein hubs and network alterations in Alzheimer’s disease” Acta Neuropathological Communications 2018, 6:19.
400. Wen, L.; Liu, D.; Zheng, Y.; Huang, K.; Cao, X.; Song, J.; Wang, P. G. “A one-step chemoenzymatic labeling Strategy for probing sialylated Thomsen-Friedenreich Antigen” ACS Central Science 2018, 4(4), 451-457.
399. Wen, F.; Li, L.; Zhao, N.; Chiang, M. J.; Xie, H.; Cooley, J.; Webby, R.; Wang, P. G.; Wan, X. F. “AY161F Hemagglutinin Substitution Increases Thermostability and Improves Yields of 2009 H1N1 Influenza A Virus in Cells”. Journal of Virology 2018, Jan 2;92(2).
398. Yang, B., Tang, S., Ma, C., Li, S.T., Shao, G.C., Dang, B., DeGrado, W.F., Dong, M.Q., Wang, P.G., Ding, S. and Wang, L. "Spontaneous and specific chemical cross-linking in live cells to capture and identify protein interactions." Nature Communications 2017, 2240.
397. Li, S., Wang, S., Fu, X., Liu, X.W., Wang, P. G. and Fang, J. "Sequential one-pot multienzyme synthesis of hyaluronan and its derivative." Carbohydrate Polymers 2017, 221-227.
396. Aguilar, A. L., Hou, X., Wen, L., Wang, P. G. and Wu, P. "A Chemoenzymatic Histology Method for O- GlcNAc Detection." ChemBioChem 2017, 2416-2421.
395. Zang, L., Kondengaden, S.M., Zhang, Q., Li, X., Sigalapalli, D.K., Kondengadan, S.M., Huang, K., Li, K.K., Li, S., Xiao, Z. and Wen, L., Wang, P.G. "Structure based design, synthesis and activity studies of small hybrid molecules as HDAC and G9a dual inhibitors." Oncotarget 2017, 63187.
394. Gashash, E.A., Aloor, A., Li, D., Zhu, H., Xu, X.Q., Xiao, C., Zhang, J., Parameswaran, A., Song, J., Ma, C. and Xiao, W. and Wang, P. G. "An Insight into Glyco-Microheterogeneity of Plasma von Willebrand Factor by Mass Spectrometry." Journal of Proteome Research 2017, 3348-3362.
393. Zhou, J., Liu, Y., Zhu, H., Zhu, H. and Wang, P. G. "Synthesis of silodosin glucuronide and its deuterated counterpart: solving a problematic O-glycosylation of a nitrogen-containing molecule." Heterocyclic Communications 2017, 187-195.
392. Jiang, K., Zhu, H., Li, L., Guo, Y., Gashash, E., Ma, C., Li, J., Zhang, L. and Wang, P.G. "Sialic acid linkage-specific permethylation for improved profiling of protein glycosylation by MALDI-TOF MS." Analytica Chimica Acta 2017, 981, 53-61.
391. Wu, Z., Liu, Y., Li, L., Wan, X.F., Zhu, H., Guo, Y., Wei, M., Guan, W. and Wang, P.G. "Decoding glycan protein interactions by a new class of asymmetric N-glycans." Organic & Biomolecular Chemistry 2017, 8946-8951.
390. Yu, H.; Li, Y.; Wu, Z.; Li, L.; Zeng, J., Zhao; C., Wu, Y.; Tasnima, N.; Wang, J.; Liu, H.; Gadi, M.R.; Wang, P.G.; X, Chen. "H. pylori α1–3/4-fucosyltransferase (Hp3/4FT)-catalyzed one-pot multienzyme (OPME) synthesis of Lewis antigens and human milk fucosides." Chemical Communications 2017, 11012-11015.
389. Calderon, A.D., Li, L. and Wang, P.G. "FUT8: from biochemistry to synthesis of core-fucosylated N-glycans." Pure and Applied Chemistry 2017, 911-920.
388. Song, Q.; Wu, Z.; Fan, Y.; Song, W.; Zhang, P.; Wang, L.; Wang, F.; Xu, Y.; Wang, P. G.; Cheng, J. "Production of homogeneous glycoprotein with multisite modifications by an engineered N-glycosyltransferase mutan". Journal of Biological Chemistry 2017, 292, 8856.
387. Ma, J.; Wang, Q.; Huang, Z.; Yang, X.; Nie, Q.; Hao, W.; Wang, P. G.; Wang, X. "Glycosylated platinum (IV) complexes as substrates for glucose transporters (GLUTs) and organic cation transporters (OCTs) exhibited cancer targeting and human serum albumin binding properties for drug delivery". Journal of Medicinal Chemistry 2017. 60, 5736.
386. Jiang, K.; Aloor, A.; Qu, J.; Xiao, C.; Wu, Z.; Ma, C.; Zhang, L.; Wang, P. G. "Rapid and sensitive MALDI MS analysis of oligosaccharides by using 2-hydrazinopyrimidine as a derivative reagent and co-matrix". Analytical and Bioanalytical Chemistry 2017, 409, 421.
385. Zhang, G. -Q.; Jin, H.; Zhao, Y.; Guo, L.; Gao, X.; Wang, X.; Tie, S.; Shen, J.; Wang, P. G.; Gan, H.; Cui, H.; Zhao, W. “An efficient anticoagulant candidate: Characterization, synthesis and in vivo study of a fondaparinux analogue Rrt1.17”. European Journal of Medicinal Chemistry 2017, 126, 1039.
384. Fu, X.; Shang, W.; Wang, S.; Liu, Y.; Qu, J.; Chen, X.; Wang, P. G.; Fang, J. “A general strategy for the synthesis of homogeneous hyaluronan conjugates and their biological applications.” Chemical Communications 2017, 53, 3555.
383. Ma, J.; Yang, X.; Hao, W.; Huang, Z.; Wang, X.; Wang, P. G. “Mono-functionalized glycosylated platinum(IV) complexes possessed both pH and redox dual-responsive properties: Exhibited enhanced safety and preferentially accumulated in cancer cells in vitro and in vivo”. European Journal of Medicinal Chemistry 2017, 128, 45.
382. Zhu, H.; Li, X.; Qu, J.; Xiao, C.; Jiang, K.; Gashash, E.; Liu, D.; Song, J.; Cheng, J.; Ma, C.; Wang, P. G. “Diethylaminoethyl sepharose (DEAE-sepharose) microcolumn for enrichment of glycopeptides”. Analytical and Bioanalytical Chemistry 2017, 409, 511.
381. Jiang, K.; Zhu, H.; Xiao, C.; Liu, D.; Edmunds, G.; Wen, L.; Ma, C.; Li, J.; Wang, P. G. “Solid-phase reductive amination for glycomic analysis”. Analytica Chimica Acta 2017, 962, 32.
380. Xu, Y.; Wu, Z.; Zhang, P.; Zhu, H.; Zhu, H.; Song, Q.; Wang, L.; Wang, F.; Wang, P. G.; Cheng, J. “A novel enzymatic method for synthesis of glycopeptides carrying natural eukaryotic N-glycans.” Chemical Communications 2017, 53, 9075.
379. Santra, A.; Li, Y.; Yu, H.; Slack, T. J.; Wang, P. G.; Chen, X. “Highly efficient chemoenzymatic synthesis and facile purification of a-Gal pentasaccharyl ceramide Gala3nLc4bCer.” Chemical Communications 2017, 53, 8280.
378. Liu, Y.; Wang, Y.; Yu, F.; Zhang, Z.; Yang, Z.; Zhang, W.; Wang, P. G.; Zhao, W. “Potentiating the immune response of MUC1-based antitumor vaccines using a peptide-based nanovector as a promising vaccine adjuvant”. Chemical Communications 2017, 53, 9486.
377. Wu, Z.; Liu, Y.; Ma, C.; Li, L.; Bai, J.; Byrd-Leotis, L.; Lasanajak, Y.; Guo, Y.; Wen, L.; Zhu, H.; Song, J.; Li, Y.; Steinhauer, D. A.; Smith, D. F.; Zhao, B.; Chen, X.; Guan, W.; Wang, P. G. “Identification of the binding roles of terminal and internal glycan epitopes using enzymatically synthesized N-glycans containing tandem epitopes”. Organic and Biomolecular Chemistry 2016, 14, 11106.
376. Kondengaden, S. M.; Luo, L. F.; Huang, K.; Zhu, M.; Zang, L.; Bataba, E.; Wang, R.; Luo, C.; Wang, B.; Li, K. K.; Wang, P. G. “Discovery of novel small molecule inhibitors of lysine methyltransferase G9a and their mechanism in leukemia cell lines”. European Journal of Medicinal Chemistry 2016, 122, 382.
375. Li, J.; Wang, J.; Wen, L.; Zhu, H.; Li, S.; Huang, K.; Jiang, K.; Li, X.; Ma, C.; Qu, J.; Parameswaran, A.; Song, J.; Zhao, W.; Wang, P. G. “An OGA-resistant probe allows specific visualization and accurate identification of O-GlcNAc-modified proteins in cells”. ACS Chemical Biology 2016, 11, 3002.
374. Liu, Y.; Wen, L.; Li, L.; Gadi, M. R.; Guan, W.; Huang, K.; Xiao, Z.; Wei, M.; Ma, C.; Zhang, Q.; Yu, H.; Chen, X.; Wang, P. G.; Fang, J. “A general chemoenzymatic strategy for the synthesis of glycosphingolipids”. European Jourrnal of Organic Chemistry 2016, 25, 4315.
373. Wen, L.; Huang, K.; Zheng, Y.; Liu, Y.; Zhu, H.; Wang, P. G. “A two-step strategy for the preparation of 6-deoxy-l-sorbose.” Bioorganic and Medicinal Chemistry Letters 2016, 26, 4358.
372. Wen, L.; Zheng, Y.; Jiang, K.; Zhang, M.; Kondengaden, S. M.; Li, S.; Huang, K.; Li, J.; Song, J.; Wang, P. G. “Two-step chemoenzymatic detection of N-acetylneuraminic acid-a (2-3)-galactose glycans”. Journal of American Chemical Society 2016, 138, 11473.
371. Wen, L.; Huang, K.; Zheng, Y.; Fang, J.; Kondengaden, S. M.; Wang, P. G. “Two-step enzymatic synthesis of 6-deoxy-L-psicose”. Tetrahedron Letters 2016, 57, 3819.
370. Wu, Z.; Jiang, K.; Zhu, H.; Ma, C.; Yu, Z.; Li, L.; Guan, W.; Liu, Y.; Zhu, H.; Chen, Y.; Li, S.; Li, J.; Cheng, J.; Zhang, L.; Wang, P. G. “Site-directed glycosylation of peptide/protein with homogeneous O-linked eukaryotic N-glycans”. Bioconjugate Chemistry 2016, 27, 1972.
369. Shang, W.; Zhai, Y.; Ma, Z.; Yang, G.; Ding, Y.; Han, D.; Li, J.; Zhang, H.; Liu, J.; Wang, P. G.; Liu, X. W.; Chen, M. “Production of human blood group B antigen epitope conjugated protein in Escherichia coli and utilization of the adsorption blood group B antibody”. Microbial Cell Factories 2016, 15, 138.
368. Xiao, Z.; Guo, Y.; Liu, Y.; Li, L.; Zhang, Q.; Wen, L.; Wang, X.; Kondengaden, S. M.; Wu, Z.; Zhou, J.; Cao, X.; Li, X.; Ma, C.; Wang, P. G. “Chemoenzymatic synthesis of a library of human milk oligosaccharides”. Journal of Organic Chemistry 2016, 81, 5851.
367. Wen, L.; Zheng, Y.; Li, T.; Wang, P. G. “Enzymatic synthesis of 3-deoxy-D-manno-octulosonic acid (KDO) and its application for LPS assembly”. Bioorganic and Medicinal Chemistry Letters 2016, 26, 2825.
366. Zhang, H.; Wang, B.; Ma, Z.; Wei, M.; Liu, J.; Li, D.; Zhang, H.; Wang, P. G.; Chen, M. “L-rhamnose enhances the immunogenicity of melanoma-associated antigen A3 for stimulating antitumor immune responses”. Bioconjugate Chemistry 2016, 27, 1112.
365. Jiang, K.; Bai, B.; Ta, Y.; Zhang, T.; Xiao, Z.; Wang, P. G.; Zhang, L. “O-GlcNAc regulates NEDD4-1 stability via caspase-mediated pathway”. Biochemical and Biophysical Research Communications 2016, 471, 539.
364. Ma, J.; Wang, Q.; Yang, X.; Hao, W.; Huang, Z.; Zhang, J.; Wang, X.; Wang, P. G. “Glycosylated platinum(IV) prodrugs demonstrated significant therapeutic efficacy in cancer cells and minimized side-effects”. Dalton Transactions 2016, 45, 11830.
363. Wang, Q.; Huang, Z.; Ma, J.; Lu, X.; Zhang, L.; Wang, X.; Wang, P. G. “Design, synthesis and biological evaluation of a novel series of glycosylated platinum(iv) complexes as antitumor agents”. Dalton Transactions 2016, 45, 10366.
362. Liu, Y.; Zhang, W.; He, Q.; Yu, F.; Song, T.; Liu, T.; Zhang, Z.; Zhou, J.; Wang, P. G.; Zhao, W. “Fully synthetic self-adjuvanting MUC1-fibroblast stimulating lipopeptide 1 conjugates as potential cancer vaccines”. Chemical Communications 2016, 52, 10886.
361. Wang, J.; Wang, X.; Zhao, Y.; Ma, X.; Wan, Y.; Chen, Z.; Chen, H.; Gan, H.; Li, J.; Li, L.; Wang, P. G. “Synthesis and biological evaluation of d-gluconhydroximo-1, 5-lactam and its oxime-substituted derivatives as pharmacological chaperones for the treatment of Gaucher disease”. MedChemComm. 2016, 7, 365.
360. Jiang, K.; Gao, Y.; Hou, W.; Tian, F.; Ying, W.; Li, L.; Bai, B.; Hou, G.; Wang, P. G.; Zhang, L. “Proteomic analysis of O-GlcNAcylated proteins in invasive ductal breast carcinomas with and without lymph node metastasis”. Amino Acids 2016, 48, 365.
359. Wen, L.; Huang, K.; Liu, Y.; Wang P. G. “Facile enzymatic synthesis of phosphorylated ketopentoses”. ACS Catalysis 2016, 6, 1649.
358. Li, S.; Zhu, H.; Wang, J.; Wang, X.; Li, X.; Ma, C.; Wen, L.; Yu, B.; Wang, Y.; Li, J.; Wang, P. G. “Comparative analysis of Cu(I)-catalyzed alkyne-azide cycloaddition (CuAAC) and strain-promoted alkyne-azide cycloaddition (SPAAC) in O-GlcNAc proteomics.” Electrophoresis 2016, 37, 1431.
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